Current Issues

Global Journal of Pharmaceutical and Scientific Research (GJPSR)

Abstract

ARTIFICIAL INTELLIGENCE IN TOPICAL DOSAGE FORM DEVELOPMENT

1 Pallavi Tiwari, 2Vimal K Yadav, 2Vishnu Prasad Yadav, 2Vineet Bharti, 2Kunal Agam, 3Maya Sharma, 4Rahul Maurya
1. Department of Chemistry, KAPG College, Prayagraj, U.P.- 211002 India. 2. Institute of Pharmacy, Dr. Rammanohar Lohia Avadh University, Ayodhya, Uttar Pradesh, India 3. Pacific College of Pharmacy, Pacific Higher Education and Research University Udaipur, Rajasthan 313003, India. 4. National Ayurveda Research Institute for Panchakarma, Cheruthuruthy, Thrissur, Kerala, 67953, India

Abstract

In pharmaceutical research and development, artificial intelligence (AI) has become a game-changing tool that provides creative answers to problems with dosage form optimization and drug formulation. The application of AI approaches to topical dosage form development is examined in this work, with a particular emphasis on formulations intended for transdermal, ophthalmic, and dermatological delivery systems. By utilizing artificial intelligence (AI) algorithms like machine learning, deep learning, and computer modeling, scientists can accelerate the drug formulation process, improve treatment efficacy, and reduce side effects. The application of artificial intelligence (AI) has made it possible to anticipate physicochemical qualities, identify the best excipients, and optimize formulations to meet patient needs and specific therapeutic targets. AI also helps in the development of innovative drug delivery methods with enhanced bioavailability and regulated release profiles, such as hydrogels and nanocarriers. Notwithstanding noteworthy progress, certain obstacles still exist, such as the requirement for extensive data sets, the verification of models produced by AI, and regulatory concerns. Future application of AI technology could transform the creation of topical dosage forms, resulting in formulations that are safer, more effective, and more patient-centered.
Keyword: Artificial Intelligence, topical dosage form development, machine learning, deep learning, and computational modeling